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发表于 2009-4-28 00:39:13
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分期
Stages of Rheumatoid Arthritis
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- Stage I:早期
- represents synovitis:
- synovial membrane becomes hyperemic and edematous with foci
of infiltrating small lymphocytes;
- joint effussions w/ high cell count (5,000 to 60,000 per mm3)
- x-rays will as yet show no destructive changes, but soft tissue
swelling or Osteoporosis may be seen;
- Stage II:中期
- inflammed synovial tissue now proliferates & begins to grow into joint
cavity across articular cartilage, which it gradually destroys;
-narrowing of joint due to loss of articular cartilage;
- Stage III:晚期
- pannus of Synovium;
- eroded articular cartilage & exposed sub-chondral bone;
- x-rays will show extensive cartilage loss, erosions around the margins
of joint, and deformities may have become apparent;
- Stage IV:缓解稳定期
- end stage disease;
- inflammatory process is subsiding;
- fibrous or bony ankylosing of joint will end its functional life;
- subcutaneous nodules associated w/ severe disease;
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Original Text by Clifford R. Wheeless, III, MD |
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